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[Cardiac myopathy due to overt hypothyroidism]
B Harbeck1, M J Berndt1, H Lehnert1
1Medizinische Klinik 1, Universitätsklinikum Schleswig-Holstein Campus Lübeck.
Deutsche Medizinische Wochenschrift (1946)
|February 27, 2014
Summary
Severe hypothyroidism can manifest as muscle weakness and cardiac issues. Prompt treatment with levothyroxine can lead to recovery.
Area of Science:
- Endocrinology
- Cardiology
- Neurology
Background:
- Hypothyroidism is a common endocrine disorder.
- Severe hypothyroidism can lead to various systemic complications.
- Myopathy and cardiac involvement are less common presentations.
Observation:
- A 51-year-old male presented with fatigue, proximal muscle weakness, hair loss, and weight gain.
- Physical examination revealed pretibial myxedema and dry skin.
- Laboratory tests showed elevated cardiac enzymes and marked hypothyroidism.
Findings:
- Investigations including ECG, echocardiography, and imaging were normal.
- Thyroid ultrasound indicated Hashimoto thyroiditis.
- Diagnosis of overt hypothyroidism with myxedema and rhabdomyolysis was confirmed.
Implications:
- This case highlights that severe overt hypothyroidism can present primarily as myopathy with myositis and cardiac involvement.
- Early diagnosis and treatment are crucial for managing hypothyroidism-related complications.
- Further research may explore the mechanisms linking hypothyroidism to myopathy and cardiac dysfunction.
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