Related Experiment Video
Updated: May 2, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Transient cortical blindness after coronary artery angiography
Michał Terlecki1, Wiktoria Wojciechowska1, Marek Rajzer1
11 Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland.
Insights
Transient cortical blindness is a rare complication following coronary angiography. This case highlights a potential neurotoxic effect of X-ray contrast media, with symptoms resolving quickly.
Area of Science:
- Cardiology
- Neurology
- Ophthalmology
Background:
- Coronary angiography is standard for diagnosing ischemic heart disease, with high procedure volumes.
- Cerebral complications like stroke are rare after coronary procedures.
- Transient cortical blindness is an uncommon complication, typically associated with cerebral angiography.
Observation:
- A 32-year-old man with ventricular arrhythmias and reduced ejection fraction underwent coronary angiography.
- The patient experienced transient cortical blindness immediately post-procedure.
- No arterial lesions were identified, and neurological/ophthalmological exams were normal.
Findings:
- Transient cortical blindness occurred directly after coronary angiography.
- The event is potentially linked to the neurotoxic effects of X-ray contrast media.
- Complete visual recovery was observed within hours.
Implications:
- This case underscores the rare but possible neurotoxicity of contrast agents used in coronary angiography.
- Prompt recognition and monitoring are crucial for managing this adverse event.
- Further research may clarify the mechanisms and risk factors for contrast-induced neurotoxicity.
Abstract:
Coronary angiography is the current gold standard for the diagnosis of ischemic heart disease and therefore the prevalence of percutaneous coronary procedures such as angiography and angioplasty is high. The occurrence of cerebral complications after coronary angiography and coronary angioplasty is low and it mainly includes transient ischemic attack and stroke. The prevalence of transient cortical blindness after X-ray contrast media is low and it is usually seen after cerebral angiography. Until now only a few cases of transient cortical blindness have been described after coronary artery angiography. Regarding the spread of coronary angiography worldwide and in Poland this complication is uniquely rare. A 32-year-old man with multiple extrasystolic ventricular arrhythmia suggesting Brugada syndrome diagnosis according to morphology of the left bundle branch block and with decreased left ventricular ejection fraction was admitted to the First Department of Cardiology and Hypertension, Medical College of the Jagiellonian University in Krakow. Coronary angiography was performed in order to exclude ischemic etiology of the observed abnormalities. No arteriosclerotic lesions were found in coronary arteries. Transient cortical blindness was observed directly after angiography which may have been caused by the neurotoxic effect of the used X-ray contrast medium. In ophthalmologic and neurologic examination as well as in the cerebral computed tomography scan no pathologies were found. Visual impairment disappeared totally within several hours.
Related Concept Videos
Transient Ischemic Attack l: Introduction
Acute Coronary Syndrome I: Introduction
Visual Agnosia

