Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

1.5K
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
1.5K
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

1.8K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.8K
Esophageal Achalasia01:27

Esophageal Achalasia

45
Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide...
45
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

1.1K
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
1.1K
Gastroesophageal Reflux Disease01:25

Gastroesophageal Reflux Disease

46
Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
46
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

1.3K
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Symmetry-Breaking and Selection-Rule Relaxation in CVD-Grown Hexagonal FeTe<sub>2</sub> Probed by Angle- and Helicity-Resolved Raman Spectroscopy.

The journal of physical chemistry letters·2026
Same author

Deterministic, dynamically reconfigurable single quantum emitters enabled by tip-enhanced nano-optical trapping spectroscopy.

Nature communications·2026
Same author

Metformin Is Associated With a Reduced Risk of Gastric Cancer, but Not Dysplasia, in Patients With Diabetes.

The Korean journal of helicobacter and upper gastrointestinal research·2026
Same author

Distinct predictive factors for acute severe ulcerative colitis in East Asian and Western populations.

Inflammatory bowel diseases·2026
Same author

Ion-Gel-Assisted MoS<sub>2</sub> Transfer Method for Low-Voltage, High-Performance MoS<sub>2</sub>/ITZO Heterojunction Phototransistor Application.

Micromachines·2026
Same author

Pontine Microtubular Signal Intensity in Hemifacial Spasm: Association with Outcome After Microvascular Decompression Surgery.

Life (Basel, Switzerland)·2026

Related Experiment Video

Updated: May 2, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

974

Barrett esophagus in Asia: same disease with different pattern.

Hyun Seok Lee1, Seong Woo Jeon1

  • 1Department of Internal Medicine, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea.

Clinical Endoscopy
|February 27, 2014
PubMed
Summary

Barrett esophagus (BE) in Asia presents differently than in the West, with lower esophageal adenocarcinoma (EAC) rates despite rising gastroesophageal reflux disease (GERD). Further research is needed to understand these distinct patterns.

Keywords:
Barrett esophagusPrevalenceRisk factors

More Related Videos

An Immunofluorescent Method for Characterization of Barrett&#8217;s Esophagus Cells
08:54

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells

Published on: July 20, 2014

13.1K
Diagnosis of Neoplasia in Barrett&#8217;s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

10.5K

Related Experiment Videos

Last Updated: May 2, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

974
An Immunofluorescent Method for Characterization of Barrett&#8217;s Esophagus Cells
08:54

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells

Published on: July 20, 2014

13.1K
Diagnosis of Neoplasia in Barrett&#8217;s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

10.5K

Area of Science:

  • Gastroenterology
  • Oncology
  • Epidemiology

Background:

  • Barrett esophagus (BE) is linked to chronic gastroesophageal reflux disease (GERD) and esophageal adenocarcinoma (EAC).
  • BE and EAC prevalence is rising in the West.
  • Asian countries show increasing GERD but low BE/EAC rates, suggesting different disease patterns.

Purpose of the Study:

  • To investigate the distinct epidemiological patterns of Barrett esophagus in Asia compared to Western countries.
  • To identify risk factors and characteristics of BE in the Asian population.

Main Methods:

  • Review of existing literature on Barrett esophagus, GERD, and EAC in Asian and Western populations.
  • Analysis of reported risk factors and prevalence rates specific to Asia.
  • Comparison of BE subtypes, such as short-segment BE, in Asian patients.

Main Results:

  • Despite increasing GERD prevalence in Asia, rates of BE and EAC remain low.
  • Known Western risk factors for BE are present in Asia, alongside others like kyphosis.
  • Most Asian BE patients present with short-segment BE.
  • Helicobacter pylori infection is more common in Asia.

Conclusions:

  • Barrett esophagus in Asia exhibits unique epidemiological characteristics compared to the West.
  • Further prospective studies are recommended to fully elucidate these differences and their clinical implications.