Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

408
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
408
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

1.0K
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
1.0K
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

967
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
967
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

554
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
554
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

410
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
410
Special considerations while measuring pulse01:13

Special considerations while measuring pulse

1.0K
Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Upper extremity bursitis.

American family physician·1997
Same author

Efficacy of strength training in prepubescent to early postpubescent males and females: effects of gender and maturity.

Pediatric rehabilitation·1997
Same author

Patient profile, referral sources, and consultant utilization in a primary care sports medicine clinic.

The Journal of family practice·1996
Same author

Evaluation of pediatric foot problems: Part II. The hindfoot and the ankle.

American family physician·1996
Same author

Evaluation of pediatric foot problems: Part I. The forefoot and the midfoot.

American family physician·1996
Same author

Lower extremity bursitis.

American family physician·1996

Related Experiment Video

Updated: May 2, 2026

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
08:26

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

5.3K

Special considerations for the pediatric running population.

C W Zukowski1, W A Lillegard1

  • 1Primary Care Sports Medicine, Department of Family Practice, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

Journal of Back and Musculoskeletal Rehabilitation
|February 28, 2014
PubMed
Summary

Pediatric running is increasing, presenting unique health risks and concerns for young athletes. This guide helps primary health care providers manage these specific issues in child runners.

Keywords:
Aerobic exerciseChildrenExerciseExercise physiologyInjuriesRunning

More Related Videos

An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field
06:52

An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field

Published on: May 26, 2020

10.1K
Influence of Step-Width Manipulation on Running Biomechanics
06:53

Influence of Step-Width Manipulation on Running Biomechanics

Published on: February 28, 2025

1.1K

Related Experiment Videos

Last Updated: May 2, 2026

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
08:26

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

5.3K
An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field
06:52

An Inertial Measurement Unit Based Method to Estimate Hip and Knee Joint Kinematics in Team Sport Athletes on the Field

Published on: May 26, 2020

10.1K
Influence of Step-Width Manipulation on Running Biomechanics
06:53

Influence of Step-Width Manipulation on Running Biomechanics

Published on: February 28, 2025

1.1K

Area of Science:

  • Pediatric sports medicine
  • Running biomechanics in children

Background:

  • Increasing participation of children in running sports at younger ages.
  • Recognition of both shared and unique health concerns in pediatric runners compared to adults.

Purpose of the Study:

  • To inform primary health care providers about the distinct aspects of pediatric running.
  • To outline differences in risks, injuries, and treatments for young runners.

Main Methods:

  • Review of current literature on pediatric running injuries and health.
  • Synthesis of information relevant to primary care practice.

Main Results:

  • Children face specific risks and injuries not typically seen in adult runners.
  • Treatment and management strategies may differ significantly for pediatric populations.

Conclusions:

  • Primary health care providers need specialized knowledge to address the health needs of pediatric runners.
  • Early identification and appropriate management are crucial for the well-being of young athletes in running sports.