Related Experiment Video
Updated: May 2, 2026

Simple and Effective Procedure for Hemostasis in Mouse Arteries
Published on: November 28, 2025
A new hemostatic clip for endoscopic surgery that can maintain blood flow after clipping
Kyoung Won Nam1, Sang Bong Lee1, In Young Kim1
1Kyoung Won Nam, In Young Kim, Department of Biomedical Engineering, Hanyang University, Seoul 133-791, South Korea.
Aim:
To develop a new hemostatic device for endoscopic surgery that can control the bleeding without completely occluding the bleeding vessel.
Methods:
A hemostatic clip and its applier that can stanch bleeding while maintaining blood flow through the clipped vessel was introduced, and the performance of the proposed clip was evaluated using in vitro and in vivo experiments.
Results:
During in vitro experiments, no leakage was found after clipping at cuts made in artificial vessels, and flow was maintained through the clipped artificial vessels. In experiments on rats, all the implanted clips occluded the target vessels successfully, and no bleeding or tissue damage was observed at the operative site after the rats were euthanized on postoperative day 7. In experiments on pigs, bleeding stopped immediately after partial clipping of a damaged vessel, and some amount of blood flow was consistently maintained through the clipped vessel after hemostasis.
Conclusion:
We believe that the proposed hemostatic clip and clip applier can enhance patient safety during laparoscopic surgery.
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