Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cerebral Hemispheres01:05

Cerebral Hemispheres

3.8K
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
3.8K
Auditory Pathway01:15

Auditory Pathway

7.1K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
7.1K
Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

6.0K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
6.0K
Hearing01:31

Hearing

48.0K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
48.0K
Anatomy of the Ear01:16

Anatomy of the Ear

11.5K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
11.5K
Lateralization01:28

Lateralization

1.3K
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional Outcome Prediction in Young Adults With Mental Health Symptoms Using Machine Learning and Large Language Models: Longitudinal Observational Study.

JMIR mental health·2026
Same author

Childhood maltreatment is linked to transdiagnostic age- and sex-specific cortical thinning and reduced amygdalar volume in young adults.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·2026
Same author

[Long-term treatment of severe depression].

Fortschritte der Neurologie-Psychiatrie·2026
Same author

Acute placebo responsiveness predicts longitudinal expectation effects in antidepressant treatment.

Translational psychiatry·2026
Same author

Transcranial alternating current stimulation over left DLPFC modulates feedback processing: a simultaneous tACS-fMRI study.

Translational psychiatry·2026
Same author

From surface to depth: Using deep learning to predict striatal fMRI reward signaling from EEG.

Imaging neuroscience (Cambridge, Mass.)·2026

Related Experiment Video

Updated: May 2, 2026

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging
10:09

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging

Published on: September 12, 2012

13.4K

Interhemispheric auditory connectivity: structure and function related to auditory verbal hallucinations.

Saskia Steinmann1, Gregor Leicht1, Christoph Mulert1

  • 1Psychiatry Neuroimaging Branch, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf Hamburg, Germany.

Frontiers in Human Neuroscience
|February 28, 2014
PubMed
Summary

Auditory verbal hallucinations (AVH) in schizophrenia are linked to altered interhemispheric auditory pathways. Increased pathway integrity correlates with AVH severity and impacts speech perception, revealing a key structure-function relationship.

Keywords:
auditory cortexauditory-verbal hallucinationsneuroimagingschizophreniastructural and functional interhemispheric connectivity

More Related Videos

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

9.8K
Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
09:54

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Published on: May 10, 2019

11.5K

Related Experiment Videos

Last Updated: May 2, 2026

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging
10:09

Mapping the After-effects of Theta Burst Stimulation on the Human Auditory Cortex with Functional Imaging

Published on: September 12, 2012

13.4K
Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning
08:43

Combined Shuttle-Box Training with Electrophysiological Cortex Recording and Stimulation as a Tool to Study Perception and Learning

Published on: October 22, 2015

9.8K
Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
09:54

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Published on: May 10, 2019

11.5K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Imaging

Background:

  • Auditory verbal hallucinations (AVH) are a core symptom of schizophrenia.
  • Neurobiological underpinnings of AVH, including auditory cortex function and connectivity, remain debated.
  • Interhemispheric auditory pathways are hypothesized to play a role in AVH pathogenesis.

Purpose of the Study:

  • To investigate the structure-function relationship of interhemispheric auditory pathways in schizophrenia patients with and without AVH.
  • To explore how variations in these pathways relate to AVH severity and speech perception.

Main Methods:

  • Diffusion Tensor Imaging (DTI) to measure structural integrity of interhemispheric auditory pathways.
  • Dichotic Listening (DL) task to assess functional aspects of speech perception and information transfer.
  • Comparison between hallucinating patients, non-hallucinating patients, and controls.

Main Results:

  • Significant interindividual variability in the size and shape of interhemispheric auditory pathways observed.
  • Schizophrenia patients with AVH showed increased fractional anisotropy (FA) in these pathways compared to non-hallucinating patients.
  • Higher FA values correlated with increased AVH severity and influenced speech perception via information transfer.

Conclusions:

  • Alterations in the structural and functional connectivity of auditory areas, particularly interhemispheric pathways, are implicated in the pathophysiology of AVH.
  • A variable structure-function relationship exists between interhemispheric auditory pathway integrity and auditory processing in schizophrenia.
  • These findings highlight potential targets for understanding and treating AVH.