Related Experiment Video
Updated: May 2, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Acute macular neuroretinopathy in a 15-year-old boy: optical coherence tomography and visual acuity findings
Shinji Makino1, Hironobu Tampo1
1Department of Ophthalmology, Jichi Medical University, Shimotsuke, Japan.
Purpose:
To report a case of acute macular neuroretinopathy (AMN) in a 15-year-old boy.
Methods:
Images were obtained with fundus photography and optical coherence tomography (OCT).
Results:
The patient complained of blurred vision and a small central scotoma in the left eye. Left visual acuity was 0.3. Fundus photographs revealed a small dark area in the fovea of the left eye. OCT showed attenuation of the photoreceptor inner segment (IS)/outer segment (OS) line and the OS/retinal pigment epithelium (RPE) line in the left eye. One week after the initial visit, left visual acuity had improved to 0.6, and there was partial recovery of the IS/OS line with focal thinning of the OS/RPE line. One month later, left visual acuity had improved to 0.8, and OCT showed complete restoration of the IS/OS line and the OS/RPE line.
Conclusions:
To our knowledge, this is the youngest patient reported with a diagnosis of AMN. Changes in microstructural findings and visual acuity were analogous during recovery of AMN in our patient.
More Related Videos
10:14Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
07:08Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
Published on: January 10, 2019
Related Concept Videos
Diabetic Retinopathy
Glaucoma: Overview