Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Pauli Exclusion Principle03:06

The Pauli Exclusion Principle

51.7K
The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:
51.7K
Strategies of Self-Presentation I: Strategic Self-Presentation01:12

Strategies of Self-Presentation I: Strategic Self-Presentation

349
Strategic self-presentation refers to individuals' intentional efforts to influence how others perceive them. This process is employed in various social and professional settings, such as job interviews, dating, politics, and legal contexts, where individuals seek to shape impressions to gain social or material advantages. While people generally present themselves in ways that align with their authentic characteristics, external factors, such as cognitive load, can hinder their ability to...
349
Self-Presentation01:25

Self-Presentation

378
Self-presentation is a fundamental aspect of social interaction, shaping both how others perceive individuals and how they view themselves. This dynamic process influences behaviors in various social settings, often leading people to adjust their appearance, speech, and demeanor to align with their desired identity. While self-presentation can be deliberate or unconscious, it plays a critical role in interpersonal relationships and self-perception.Forms of Self-PresentationSelf-presentation can...
378
Introspection01:29

Introspection

443
Introspection, long upheld as a reliable route to self-knowledge, involves examining one's thoughts, emotions, and mental processes. It underpins many psychological practices, from mindfulness meditation to psychotherapy and self-help strategies. However, empirical evidence challenges the accuracy of introspection as a means of understanding oneself.Limitations of Introspective InsightSeminal work by Nisbett and Wilson demonstrated that individuals are frequently unaware of the true causes...
443
Strategies of Self-Presentation II: Self-Verification01:17

Strategies of Self-Presentation II: Self-Verification

274
Self-verification is a fundamental psychological drive wherein individuals seek affirmation of their self-concept from others, striving for consistency between their internal self-view and external perceptions. This drive operates even when the self-concept is negative, influencing interpersonal behavior and feedback preferences in complex and often counterintuitive ways. Unlike the self-enhancement motive, which seeks positive evaluations, self-verification prioritizes coherence and...
274
Stereotype Threat and Self-fulfilling Prophecies02:09

Stereotype Threat and Self-fulfilling Prophecies

28.1K
When we hold a stereotype about a person, we have expectations that he or she will fulfill that stereotype. A self-fulfilling prophecy is an expectation held by a person that alters his or her behavior in a way that tends to make it true. When we hold stereotypes about a person, we tend to treat the person according to our expectations. This treatment can influence the person to act according to our stereotypic expectations, thus confirming our stereotypic beliefs. Research by Rosenthal and...
28.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data- and knowledge-derived functional landscape of human solute carriers.

Molecular systems biologyยท2025
Same author

The RESOLUTE consortium: unlocking SLC transporters for drug discovery.

Nature reviews. Drug discoveryยท2020
Same author

How Phenotypic Screening Influenced Drug Discovery: Lessons from Five Years of Practice.

Assay and drug development technologiesยท2017
Same author

Linking phenotypes and modes of action through high-content screen fingerprints.

Assay and drug development technologiesยท2015
Same author

Study rules out zinc as a potential biomarker of Alzheimer's disease.

Bioanalysisยท2014
Same author

New compound could be an ideal candidate for visual restoration in patients with degenerative retinal disorders.

Future medicinal chemistryยท2014
Same journal

Indole-based carbohydrazides as potent anti-proliferative leads and tubulin polymerization inhibitors: design, synthesis, cytotoxic evaluation, <i>in silico</i> ADMET and docking studies.

Future medicinal chemistryยท2026
Same journal

Recent advances in the development of small molecule STK33 inhibitors.

Future medicinal chemistryยท2026
Same journal

Biological evaluation and molecular docking of previously reported pyrazolo-thiazole derivatives as dual ฮฑ-amylase and ฮฑ-glucosidase inhibitors.

Future medicinal chemistryยท2026
Same journal

Coumarin derivatives as antidiabetic agents: a comprehensive review on mechanistic insights, structure-activity relationships, <i>in silico</i> studies, and challenges.

Future medicinal chemistryยท2026
Same journal

Expanding the tetrazole space: medicinal chemistry, biological diversity and structure-activity relationships.

Future medicinal chemistryยท2026
Same journal

Thiazolidin-based dual Aurora kinase inhibitors with potent anticancer activity.

Future medicinal chemistryยท2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Interview: Protein Folding and Studies of Neurodegenerative Diseases
19:50

Interview: Protein Folding and Studies of Neurodegenerative Diseases

Published on: July 16, 2008

17.7K

Interview with Paul Selzer.

Paul Selzer1, James Potticary

  • 1Novartis Institutes for Biomedical Research, Basel, Switzerland. paul.selzer@novartis.com.

Future Medicinal Chemistry
|March 1, 2014
PubMed
Summary
This summary is machine-generated.

Computational chemist Paul Selzer discusses key issues and current work in computational medicinal chemistry. His insights cover advancements and challenges in drug discovery and development.

More Related Videos

Proboscis Extension Response PER Assay in Drosophila
23:42

Proboscis Extension Response PER Assay in Drosophila

Published on: April 29, 2007

30.3K
Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.1K

Related Experiment Videos

Last Updated: May 2, 2026

Interview: Protein Folding and Studies of Neurodegenerative Diseases
19:50

Interview: Protein Folding and Studies of Neurodegenerative Diseases

Published on: July 16, 2008

17.7K
Proboscis Extension Response PER Assay in Drosophila
23:42

Proboscis Extension Response PER Assay in Drosophila

Published on: April 29, 2007

30.3K
Microbial Communities in Nature and Laboratory - Interview
29:13

Microbial Communities in Nature and Laboratory - Interview

Published on: May 28, 2007

6.1K

Area of Science:

  • Computational chemistry
  • Medicinal chemistry
  • Drug discovery

Background:

  • Paul Selzer, a computational chemist with over 20 years of experience.
  • PhD in computational chemistry from the University of Erlangen-Nuremberg.
  • Currently at Novartis, focusing on computational medicinal chemistry.

Discussion:

  • Pressing issues in the computational medicinal chemistry field.
  • Current research initiatives at Novartis.
  • Future directions and challenges in the discipline.

Key Insights:

  • Selzer's extensive experience informs discussions on the field's evolution.
  • Highlights the practical applications of computational methods in drug development.
  • Emphasizes the importance of interdisciplinary collaboration.

Outlook:

  • Potential advancements in computational drug design.
  • The role of computational chemistry in accelerating pharmaceutical research.
  • Future trends and innovations in medicinal chemistry.