A comparison pressure pain threshold in pericranial and extracephalic regions in children with migraine

Gabriela Natália Ferracini1, Juliana Stuginsk-Barbosa, Fabíola Dach

  • 1Faculty of Medicine of Ribeirão Preto (FMRP-USP), Ribeirão Preto, SP, Brazil.

Insights

Children with migraine have reduced pressure pain threshold (PPT) in specific head and neck areas compared to healthy children. This finding was consistent across genders, highlighting localized pain sensitivity in pediatric migraine.

Area of Science:

  • Pediatric Neurology
  • Pain Medicine
  • Clinical Neuroscience

Background:

  • Migraine is associated with reduced pressure pain threshold (PPT) in children.
  • PPT variations exist based on age, sex, and body region.
  • Lack of consensus necessitates further investigation into PPT in pediatric migraine.

Purpose of the Study:

  • To evaluate the pressure pain threshold (PPT) in children aged 6-12 years with migraine without aura.
  • To compare PPT between children with and without migraine, considering gender and anatomical sites.

Main Methods:

  • Fifty children diagnosed with migraine without aura and 50 healthy children were enrolled.
  • Pressure pain threshold (PPT) was measured using an algometer at nine bilateral anatomical sites.
  • Data was analyzed to compare PPT values between groups and across different regions and genders.

Main Results:

  • Children with migraine exhibited lower PPT at the occipital muscle insertion and anterior C5-C7 regions compared to controls.
  • No significant PPT differences were observed in other evaluated regions between the groups.
  • Both girls and boys with migraine showed reduced PPT in at least one body region.

Conclusions:

  • Pericranial and cervical regions demonstrated lower PPT in children with migraine compared to extracephalic sites.
  • Localized hypersensitivity in head and neck areas is characteristic of pediatric migraine.
  • Findings contribute to understanding pain mechanisms in childhood migraine.
Abstract