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Updated: May 2, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Cardiac restriction secondary to massive calcific deposits in the left ventricular cavity
William C Roberts1, Randall L Rosenblatt2, Jong Mi Ko3
1Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas; Department of Pathology, Baylor University Medical Center, Dallas, Texas; Division of Cardiology, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas.
Insights
A massive calcific deposit in the left ventricle caused fatal diastolic heart failure in a 61-year-old woman. Surgical removal of these deposits is an effective treatment for this rare condition.
Area of Science:
- Cardiology
- Pathology
Background:
- The patient had a history of aortic coarctation repair and aortic valve replacement.
- Massive calcific deposits within the left ventricular cavity are rare.
Observation:
- Clinical and necropsy findings of a 61-year-old woman are presented.
- The patient experienced fatal left ventricular diastolic failure.
Findings:
- Left ventricular diastolic failure was secondary to massive calcific deposits.
- The exact cause of the intracavitary calcific deposits remains undetermined.
Implications:
- Surgical resection of intracavitary calcific deposits can be an effective therapy.
- Understanding the etiology of these deposits is crucial for prevention and treatment.
Abstract:
Described herein are clinical and necropsy findings in a 61-year-old woman with fatal left ventricular diastolic failure secondary to massive calcific deposits primarily within the left ventricular cavity. At age 3, an isthmic aortic coarctation was resected, and at age 44, a stenotic congenitally bicuspid aortic valve was replaced. The cause of the intracavitary calcific deposits remains unclear, but surgical resection of the deposits has been an effective form of therapy.
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