Trichophyton onychocola sp. nov. isolated from human nail

Area of Science:

• Medical Mycology
• Fungal Taxonomy
• Dermatology

Background:

• Onychomycosis is a common nail fungal infection.
• Accurate etiological diagnosis is crucial for effective treatment.
• Novel fungal species require detailed characterization for classification.

Observation:

• A novel Trichophyton species was isolated from a patient with recurrent distal lateral subungual onychomycosis.
• The isolate exhibited unique morphological and physiological characteristics.
• Phylogenetic analysis indicated a geophilic nature and close relation to existing Trichophyton species.

Findings:

• The new species, named Trichophyton onychocola sp. nov., was characterized by yellowish colonies, red reverse, positive urease, and absence of macroconidia.
• Molecular data from ITS, benA, RPB2, and act1 gene sequences supported its distinct species status.
• The fungus demonstrated growth on sterilized human hair, forming gymnothecium-like structures.

Implications:

• This finding expands the known diversity of dermatophytes.
• Trichophyton onychocola sp. nov. may be a significant etiological agent of onychomycosis.
• Further research is needed to understand its clinical relevance and treatment strategies.