A randomized trial of a prenatal genetic testing interactive computerized information aid.

Area of Science:

• Medical Genetics
• Health Informatics
• Patient Education

Background:

• Genetic screening and diagnostic concepts are complex for patients.
• Effective patient education is crucial for informed decision-making in prenatal care.
• Current standard counseling methods may have limitations in conveying detailed genetic information.

Purpose of the Study:

• To evaluate the effectiveness of an interactive computer program in enhancing patient knowledge of genetic screening and diagnostic concepts.
• To compare knowledge acquisition between patients receiving standard care and those using an interactive educational tool.

Main Methods:

• A randomized trial involving 150 women (6-26 weeks' gestation) compared standard care with provider counseling to augmented counseling using an interactive computer program.
• The computer program delivered information on genetic testing options.
• Knowledge was assessed using a 23-item test immediately and 2-4 weeks post-intervention, with scores compared via T-tests.

Main Results:

• Women using the interactive tool demonstrated significantly higher correct answer rates immediately post-intervention (69.4% vs. 46.0%, p<0.001) and at follow-up (60.6% vs. 49.7%, p=0.001).
• The educational intervention's benefit was not differentially associated with education level, health literacy, or prior provider discussions.
• High participant adherence was noted, with 82% completing the follow-up knowledge test.

Conclusions:

• Patient-directed interactive computer programs can effectively supplement provider counseling for genetic screening information.
• This technology offers a scalable solution to improve patient comprehension of genetic concepts.
• Interactive tools may enhance informed consent and patient engagement in genetic testing decisions.