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Updated: May 2, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Assessment of the myocardium with cardiac computed tomography
Benjamin Clayton1, Carl Roobottom2, Gareth Morgan-Hughes3
1Cardiology Department, X-Ray East, Derriford Hospital, Plymouth PL6 8DH, UK benjamin.clayton@nhs.net.
Insights
Cardiac computed tomography (CT) offers valuable insights into myocardial diseases, complementing cardiac magnetic resonance and echocardiography. This review explores CT
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Technology
Background:
- Myocardial disease diagnosis and management are crucial for cardiologists.
- Cardiac magnetic resonance and echocardiography are gold standards but have limitations.
- Cardiac computed tomography (CT) is established for coronary artery disease (CAD) assessment.
Purpose of the Study:
- To review the value and limitations of CT in assessing myocardial pathology.
- To highlight CT's role in myocardial sequelae of CAD and other cardiomyopathies.
- To discuss current developments in CT for myocardial imaging.
Main Methods:
- Review of existing literature on cardiac computed tomography for myocardial disease.
- Analysis of CT's capabilities in tissue characterization and spatial resolution.
- Depiction of common findings in various cardiomyopathic diseases using CT.
Main Results:
- CT provides excellent patient compatibility and tolerability.
- CT offers high spatial resolution for detailed myocardial assessment.
- CT demonstrates value in evaluating myocardial sequelae of CAD and other cardiomyopathies.
Conclusions:
- CT is a valuable, complementary tool for myocardial disease imaging.
- CT's strengths include patient tolerance and high resolution.
- Further developments are enhancing CT's role in cardiology.
Abstract:
The imaging of myocardial disease is of increasing importance for cardiologists from all subspecialties, for diagnosis, risk stratification, or to facilitate therapy. While the gold standard modalities for such assessment are cardiac magnetic resonance and echocardiography, these are not universally suitable. Cardiac computed tomography (CT), well-established for the assessment of coronary artery disease (CAD), can be of value in the assessment of myocardial pathology, due to excellent patient compatibility and tolerability, high spatial resolution, and acceptable tissue characterization. This review considers the value and limitations of CT in the assessment of the myocardial sequelae of CAD, and for patients with a variety of other cardiomyopathic diseases, depicts some of the common findings, and considers current developments in this area.
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