Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

1.1K
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
1.1K
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

1.5K
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
1.5K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

610
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
610
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

1.1K
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
1.1K
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

1.6K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.6K
Stress and Mental Health01:30

Stress and Mental Health

1.7K
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retention and Other Efficacy Outcomes With Long-Acting Injectable Buprenorphine (Buvidal<sup>®</sup>) in France: A National Retrospective Cross-Sectional Study (OPALE 2).

Substance use & addiction journal·2026
Same author

Efficacy and safety of transcranial direct current stimulation in alcohol use disorder: A randomized controlled triple-blind trial.

Addiction (Abingdon, England)·2026
Same author

Co-occurring psychiatric disorders are key determinants of disability in alcohol use disorder: a cross-sectional analysis in 157 recently detoxified patients.

Alcohol and alcoholism (Oxford, Oxfordshire)·2026
Same author

The hidden burden of narcolepsy type 1: Discordance in psychobehavioral symptoms between patient self-reports and reports from close family members and friends.

Sleep medicine·2026
Same author

Structural brain effects of alcohol use patterns in alcohol use disorder: A systematic review and Meta-analysis.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same author

The rising wave of cathinone use in people attending harm reduction facilities: a French repeated cross-sectional study (2019-2023).

Addiction science & clinical practice·2026

Related Experiment Video

Updated: May 2, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

8.4K

[Somatic consequences of cannabis use].

Olivier Cottencin1, Camille Bence2, Benjamin Rolland2

  • 1CHRU de Lille, hôpital Michel-Fontan 2, service d'addictologie, France. olivier.cottencin@chru-lille.fr

La Revue Du Praticien
|March 4, 2014
PubMed
Summary

Cannabis use poses health risks, including impaired driving and chronic issues affecting multiple body systems. While not typically lethal, its long-term effects warrant careful consideration due to potential cardiovascular, respiratory, and other health consequences.

More Related Videos

Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

1.3K
Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
06:09

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

922

Related Experiment Videos

Last Updated: May 2, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

8.4K
Administration of &#916;9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

1.3K
Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
06:09

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

922

Area of Science:

  • Medical Science
  • Public Health

Context:

  • Cannabis use is prevalent globally.
  • Understanding the health implications of cannabis is crucial for public health initiatives.

Purpose:

  • To outline the acute and chronic health problems associated with cannabis use.
  • To identify the range of adverse effects on various physiological systems.

Summary:

  • Cannabis consumption can lead to acute issues like impaired motor coordination and increased accident risk.
  • Chronic cannabis use is linked to cardiovascular, respiratory, oral, gastrointestinal, metabolic, and oncological consequences.
  • Confounding factors such as concurrent tobacco smoking may influence observed health outcomes.

Impact:

  • Informing healthcare providers and policymakers about the risks of cannabis.
  • Guiding public health messaging and harm reduction strategies related to cannabis consumption.