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Published on: September 20, 2018
Iridocorneal endothelial syndrome in a Chinese child
Wei Tang1, Qinghua Wang1, Qing Zhang1
1Department of Ophthalmology, Wuxi Second Hospital Affiliated Nanjing Medical University, Wuxi 214000, China.
Insights
This report details a rare pediatric case of iridocorneal endothelial (ICE) syndrome. Surgical intervention with mitomycin C effectively controlled intraocular pressure in the affected child.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Genetics
Background:
- Iridocorneal endothelial (ICE) syndrome is a rare spectrum of disorders affecting the anterior segment of the eye.
- It is characterized by abnormalities of the corneal endothelium, iris, and iridocorneal angle.
- ICE syndrome is typically diagnosed in adults and rarely reported in pediatric populations.
Observation:
- A 6-year-old Chinese child presented with elevated intraocular pressure.
- During follow-up, the child was diagnosed with ICE syndrome, exhibiting two iris holes in the right eye.
- Initial treatment involved medication, but surgical intervention was pursued.
Findings:
- The child underwent glaucoma filtering surgery combined with intraoperative mitomycin C.
- Post-operative management resulted in stable control of intraocular pressure.
- This case highlights a rare presentation of ICE syndrome in a pediatric patient.
Implications:
- The findings suggest that glaucoma filtering surgery with mitomycin C is an effective treatment for controlling intraocular pressure in pediatric ICE syndrome.
- Further research is warranted to understand the long-term outcomes and genetic factors associated with ICE syndrome in children.
- This case contributes to the limited literature on pediatric ICE syndrome, emphasizing the need for increased awareness among ophthalmologists.
Purpose:
We reported a rare case of ICE syndrome in a Chinese child.
Case Report:
A 6-year-old child was admitted to the ophthalmology department of the Affiliated Wuxi Second Hospital of Nanjing Medical University, complaining of elevated intraocular pressure at his first diagnosis in a local hospital. The patient was initially treated with medication. During subsequent follow up, two iris holes were seen in the patient's right eye and he was then diagnosed with ICE syndrome. The child underwent surgery combined with mitomycin C intraoperatively. The intraocular pressure was stably controlled.
Conclusion:
ICE syndrome has been rarely reported in children. Glaucoma filtering surgery combined with intraoperative administration of mitomycin is efficacious for intraocular pressure control.
