Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

88
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
88
Hepatic Encephalopathy01:29

Hepatic Encephalopathy

53
DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
53
Equilibrium and Balance01:15

Equilibrium and Balance

6.2K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
6.2K
Hyperosmolar Hyperglycemic State01:21

Hyperosmolar Hyperglycemic State

20
Hyperosmolar Hyperglycemic State, or HHS, is a serious and life-threatening complication of type 2 diabetes mellitus. It is characterized by three main features: severe hyperglycemia, profound dehydration, and elevated serum osmolality, all occurring without significant ketoacidosis.HHS typically develops in older adults or individuals with limited access to fluids. This may result from illness, cognitive impairment, or medications such as diuretics or corticosteroids. These factors reduce...
20
Graves' Disease I: Introduction01:28

Graves' Disease I: Introduction

23
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence...
23
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

26
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor,...
26

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An update on equine post-operative ileus: Definitions, pathophysiology and management.

Equine veterinary journal·2017
Same author

Histological assessment of β-amyloid precursor protein immunolabelled rectal biopsies aids diagnosis of equine grass sickness.

Equine veterinary journal·2017
Same author

Equine grass sickness: Benefits of a multifaceted research approach.

Equine veterinary journal·2016
Same author

Factors affecting the efficiency of aerosolized salbutamol delivery via a metered dose inhaler and equine spacer device.

Journal of veterinary pharmacology and therapeutics·2016
Same author

Neurodegeneration in equine grass sickness is not attributable to niacin deficiency.

Equine veterinary journal·2016
Same author

Equine asthma: An appropriate, translational and comprehendible terminology?

Equine veterinary journal·2016
Same journal

Pneumocoele sinus: Computed tomographic findings and surgical approach in a 2-year-old Cob filly.

Equine veterinary journal·2026
Same journal

Effects of flow-controlled expiration on oxygenation and early recovery in horses undergoing general anaesthesia.

Equine veterinary journal·2026
Same journal

Straight sesamoidean ligament desmopathy commonly occurs with proximal interphalangeal joint osteoarthritis.

Equine veterinary journal·2026
Same journal

Using a wearable electrocardiogram (ECG) patch adapted for 7-day monitoring in the horse.

Equine veterinary journal·2026
Same journal

Prevalence of insulin dysregulation in a sport horse population as determined by traditional and stall-side testing.

Equine veterinary journal·2026
Same journal

Diagnosis of bacteraemia in neonatal foals using 16S rRNA high-throughput sequencing.

Equine veterinary journal·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
07:31

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

Published on: November 1, 2014

11.4K

Equine grass sickness.

R S Pirie1, R C Jago, N P H Hudson

  • 1Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, Easter Bush Veterinary Campus, Midlothian, UK.

Equine Veterinary Journal
|March 4, 2014
PubMed
Summary
This summary is machine-generated.

Equine grass sickness (EGS), a nervous system disease in horses, causes severe intestinal issues due to neuronal degeneration. While the cause remains unknown, understanding EGS is crucial for equine health.

Keywords:
Clostridium botulinumFusariumKey-Gaskelldysautonomiagrass sicknesshorse

More Related Videos

Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery
08:07

Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery

Published on: October 4, 2024

956
Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

9.1K

Related Experiment Videos

Last Updated: May 2, 2026

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI
07:31

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI

Published on: November 1, 2014

11.4K
Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery
08:07

Author Spotlight: Isolation and Characterization of Equine Submucosal Enteric Glia — Implications for Preventing Postoperative Complications in Colic Surgery

Published on: October 4, 2024

956
Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
08:02

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

9.1K

Area of Science:

  • Veterinary Neurology
  • Equine Medicine
  • Pathology

Background:

  • Equine grass sickness (EGS), also known as equine dysautonomia, is a polyneuropathy impacting horses.
  • It primarily affects the autonomic and enteric nervous systems, leading to characteristic clinical signs in grazing horses.
  • Disease severity varies, correlating with the extent of neuronal degeneration in the enteric nervous system.

Purpose of the Study:

  • To review the scientific literature on Equine Grass Sickness.
  • To cover key aspects including epidemiology, pathology, diagnosis, treatment, and aetiological hypotheses.
  • To consolidate current knowledge on this complex equine neurological disease.

Main Methods:

  • Comprehensive review of existing scientific literature on Equine Grass Sickness.
  • Analysis of data related to EGS epidemiology, clinical presentation, and pathological findings.
  • Synthesis of information regarding diagnostic methods, treatment strategies, and proposed causes.

Main Results:

  • EGS is characterized by neuronal degeneration in the central and peripheral nervous systems, particularly the autonomic and enteric nervous systems.
  • Acute and subacute forms involve extensive neuronal damage leading to fatal intestinal dysmotility.
  • Chronic forms exhibit less severe degeneration, with some horses surviving.

Conclusions:

  • The precise aetiology of Equine Grass Sickness remains elusive despite extensive research.
  • Understanding the epidemiology, pathology, and clinical presentation is vital for diagnosis and management.
  • Further research into the aetiology is essential for developing effective preventative strategies and treatments for EGS.