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Drug Metabolism: Phase II Reactions

Drug Metabolism: Phase II Reactions

Phase II reactions are essential for the detoxification and elimination of drugs from the body. These reactions involve the conjugation of parent drugs or their phase I metabolites with endogenous molecules, resulting in more hydrophilic drug conjugates. The primary conjugation reactions in this phase are sulfation and glucuronidation. Both sulfation and glucuronidation typically produce biologically inactive metabolites. However, in some cases involving prodrugs, active metabolites may be...

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Updated: May 2, 2026

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells

Published on: June 16, 2022

Reply: To PMID 23773733

¹Department of General and Cardiothoracic Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, 13-1 Takara-machi, Kanazawa 920-8640, Japan.

The Annals of Thoracic Surgery

|March 4, 2014

Summary

No abstract available in PubMed .

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