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[Genital lymphedema associated with Crohn's disease]
C Garny de La Rivière1, A Caudron1, B Heyman2
1Service de dermatologie, hôpital Sud, CHU d'Amiens, avenue René Laënnec - Salouel, 80054 Amiens cedex 1, France.
La Revue De Medecine Interne
|March 4, 2014
Summary
Recurrent genital lymphedema can be an early indicator of Crohn's disease, a chronic inflammatory bowel condition. Prompt diagnosis and treatment, including corticosteroids and azathioprine, can effectively manage this extra-intestinal manifestation.
Area of Science:
- Gastroenterology
- Urology
- Dermatology
Background:
- Crohn's disease is a chronic inflammatory intestinal disorder.
- It can present with diverse extra-intestinal manifestations.
- Genital lymphedema is a rare but significant manifestation.
Observation:
- A 49-year-old male presented with a decade of recurrent febrile flares and progressive genital swelling (penis and scrotum).
- Clinical examination revealed inflammatory lymphedema of the genitalia.
- Initial urological, biological, and radiological investigations were inconclusive for other causes.
Findings:
- Metastatic Crohn's disease was diagnosed, co-occurring with severe terminal ileitis.
- Treatment with corticosteroids and azathioprine led to a marked reduction in genital lymphedema.
- This case highlights a rare presentation of Crohn's disease.
Implications:
- Genital inflammatory lymphedema warrants consideration of underlying inflammatory, infectious, or neoplastic conditions.
- In the presence of gastrointestinal symptoms, Crohn's disease should be suspected.
- Early recognition of this extra-intestinal sign can facilitate timely diagnosis and management of Crohn's disease.
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