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[Urticaria: diagnosis and treatment]
1Service de dermatologie et d'allergologie, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France; Inserm U945, laboratoire immunité et infection, 81, boulevard de l'Hôpital, 75013 Paris, France.
La Revue De Medecine Interne
|March 4, 2014
Summary
Urticaria is an inflammatory skin condition characterized by hives and angioedema. While acute urticaria may have allergic triggers, chronic urticaria is not allergic and is managed with antihistamines.
Area of Science:
- Dermatology
- Immunology
- Allergy
Context:
- Urticaria is a prevalent inflammatory skin condition.
- It manifests as transient skin/mucosal lesions (hives) or subcutaneous swelling (angioedema).
- Chronic urticaria persists for over six weeks.
Purpose:
- To define urticaria and its subtypes.
- To outline diagnostic approaches for acute and chronic urticaria.
- To detail current treatment strategies.
Summary:
- Urticaria stems from mast cell activation.
- Diagnosis relies primarily on clinical examination and patient history.
- Allergic causes are investigated for acute urticaria, but chronic forms are non-allergic.
- Treatment involves symptomatic management, primarily with second-generation antihistamines.
Impact:
- Provides a concise overview of urticaria diagnosis and management.
- Highlights the distinction between acute and chronic urticaria etiologies.
- Emphasizes the role of antihistamines as first-line therapy and outlines alternative treatments for refractory cases.
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