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Updated: May 2, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
[Prenatal three-vessel and tracheal view: normal features]
E Quarello1, J-P Bault2, R Chaoui3
1Unité d'échographies obstétricales et de diagnostic anténatal, hôpital Saint-Joseph, 26, boulevard de Louvain, 13285 Marseille cedex 08, France; Institut de médecine de la reproduction, 6, rue Rocca, 13008 Marseille, France.
Insights
Screening for congenital heart disease (CHD) in low-risk populations requires simple methods. The three-vessel and tracheal view in prenatal echocardiography offers an effective approach for assessing fetal anatomy.
Area of Science:
- Medical imaging
- Fetal medicine
- Cardiology
Background:
- Congenital heart disease (CHD) screening often targets low-risk populations, necessitating accessible and reliable methods.
- Current prenatal echocardiography primarily analyzes four chambers and great vessels, with great vessel assessment being complex and requiring multiple views.
- Standardized screening methods for fetal CHD are crucial for early detection and management.
Purpose of the Study:
- To review the features of the three-vessel and tracheal view for fetal echocardiography.
- To highlight its utility in assessing fetal thoracic structures for congenital heart disease screening.
- To emphasize the role of color Doppler in optimizing this view.
Main Methods:
- Review of anatomical features of the three-vessel and tracheal view.
- Analysis of its application in a single axial section of the fetal thorax.
- Incorporation of color Doppler mode to enhance visualization.
Main Results:
- The three-vessel and tracheal view allows simultaneous assessment of the main pulmonary artery, its branches, ductus arteriosus, aortic arches, superior vena cava, and trachea.
- This view provides an axial section of the fetal thorax, simplifying complex great vessel assessment.
- Color Doppler enhances the visualization and diagnostic information obtained from this view.
Conclusions:
- The three-vessel and tracheal view is a reproducible and easy-to-use method for fetal CHD screening.
- It offers a comprehensive assessment of key thoracic structures in a single view.
- This technique, particularly with color Doppler, improves the efficiency and accuracy of prenatal screening for congenital heart disease.
Abstract:
Congenital heart disease (CG) are mostly from a low-risk population. Their screening should be based on reproducible and easy to use methods. Prenatal echocardiographic analysis is based primarily on the analysis of the four chambers and great vessels. The study of general admission pathways generalized since the 1980s is performed on an axial section while that of great vessels is performed in most countries more recently using several views and remains difficult. We review the features, under normal circumstances, of the three-vessel and tracheal view that allows via an axial section of the fetal thorax to assess at the same time the trunk of the main pulmonary artery and its branches, the convergence of the ductus arteriosus and the aortic arches, the superior vena cava, and the trachea. Furthermore, the use of color Doppler mode optimizes the information obtained by this view.
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