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Updated: May 2, 2026

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Published on: March 20, 2017
Wernicke's encephalopathy three weeks after sleeve gastrectomy.
Rawan Saab1, Mansour El Khoury2, Said Farhat3
1Department of Internal Medicine, Division of Endocrinology, Diabetes, and Metabolism, Saint George University Medical Center, University of Balamand, Al-Kurah, North Lebanon.
Bariatric surgery can cause vitamin deficiencies, leading to serious neurologic complications like Wernicke
Area of Science:
- Bariatric Surgery
- Nutritional Deficiencies
- Neurology
Background:
- Bariatric surgeries for morbid obesity can lead to malabsorption and vitamin deficiencies.
- Neurologic complications from folate, vitamin B12, and thiamine deficiencies occur in up to 16% of patients.
- Roux-en-Y gastric bypass is most associated with these deficiencies due to its restrictive and malabsorptive nature.
Observation:
- This report details a case of rapid Wernicke's encephalopathy.
- The patient was a young female who underwent Sleeve gastrectomy (SG).
- The condition was caused by a thiamine deficiency.
Findings:
- Sleeve gastrectomy (SG), a restrictive bariatric surgery, can also lead to severe thiamine deficiency.
- Rapid Wernicke's encephalopathy developed in a young female patient post-SG.
- This highlights that even restrictive surgeries carry risks of neurologic complications.
Implications:
- Wernicke's encephalopathy is a critical neurologic complication of thiamine deficiency post-bariatric surgery.
- Early diagnosis and treatment are crucial for patients undergoing any form of bariatric surgery.
- Further research is needed to understand and mitigate these risks, even with less malabsorptive procedures like SG.
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