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Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
Published on: November 4, 2022
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[Partial splenectomy in sickle cell disease]
A I Gutiérrez Díaz1, E Svarch1, A Arencibia Núñez1
1Instituto de Hematología e Inmunología, La Habana, Cuba.
Anales De Pediatria (Barcelona, Spain : 2003)
|March 4, 2014
Summary
Partial splenectomy in sickle cell disease is safe, with no increased clinical events compared to non-splenectomized patients, though hepatic sequestration crises were more frequent.
Area of Science:
- Hematology
- Pediatric Surgery
Background:
- Total splenectomy in sickle cell disease (SCD) carries high risks of sepsis.
- Partial splenectomy outcomes in SCD are less understood.
- This study compares clinical and lab results of partial splenectomy versus no splenectomy in SCD patients.
Purpose of the Study:
- To evaluate the safety and clinical outcomes of partial splenectomy in pediatric sickle cell disease patients.
- To compare patients who underwent partial splenectomy with a control group of non-splenectomized patients.
Main Methods:
- A retrospective study of 54 SCD patients who underwent partial splenectomy in childhood.
- Comparison with 54 randomly selected non-splenectomized SCD patients.
- Analysis of clinical and laboratory data, including postoperative complications and incidence of clinical events.
Main Results:
- Partial splenectomy, often for splenic sequestration crisis, was performed at a mean age of 4.1 years.
- Common complications included fever of unknown origin and acute chest syndrome.
- Leukocytes, neutrophils, and platelets increased post-splenectomy, with neutrophils and platelets remaining elevated compared to controls.
- Hepatic sequestration crisis was more frequent in the partial splenectomy group.
Conclusions:
- Partial splenectomy is a safe procedure for pediatric sickle cell disease patients.
- No significant differences in clinical events were observed between partial splenectomy and non-splenectomized groups, except for a higher incidence of hepatic sequestration crisis.
