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Related Concept Videos

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Introduction to the Human Microbiota01:22

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Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
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Microbiota of the Large Intestine01:27

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The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
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Mutualism is a symbiotic interaction in which all participating organisms benefit. These relationships can be obligate or facultative and are fundamental to ecosystem functions across diverse biological systems.Plant–Fungi MutualismOne well-known example is the association between plant roots and mycorrhizal fungi, such as Rhizophagus species. The fungal hyphae penetrate the root hairs and the epidermis, forming an extensive hyphal network that establishes a symbiotic association. Through...
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Analysis of Interactions between Endobiotics and Human Gut Microbiota Using In Vitro Bath Fermentation Systems
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Gut ecosystem: how microbes help us.

R Martín1, S Miquel1, J Ulmer1

  • 1INRA, UMR1319 Micalis, Domaine de Vilvert, 78350 Jouy-en-Josas, France AgroParisTech, UMR Micalis, Domaine de Vilvert, 78350 Jouy-en-Josas, France.

Beneficial Microbes
|March 4, 2014
PubMed
Summary
This summary is machine-generated.

The human gut microbiome, comprising trillions of microorganisms, plays a crucial role in health. This review highlights the beneficial interactions between gut bacteria, probiotics, and the host, essential for maintaining homeostasis.

Keywords:
crosstalk bacteria-hosthuman healthimmunomodulationmicrobiota

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Area of Science:

  • Microbiology
  • Human Physiology
  • Gastroenterology

Background:

  • The human gut hosts a complex microbial ecosystem (10^13-10^14 microorganisms).
  • The role of gut bacteria in human health and disease is increasingly recognized.
  • Dietary microbes, including probiotics, transit the gut and can confer health benefits.

Purpose of the Study:

  • To review recent findings on interactions between commensal and probiotic bacteria.
  • To explore the crosstalk between gut microbes and the host.
  • To emphasize the cooperative status in healthy individuals and its role in homeostasis.

Main Methods:

  • Literature review of recent scientific findings.
  • Synthesis of research on microbial interactions within the gut.
  • Analysis of host-microbe communication.

Main Results:

  • Gut microbes provide essential nutrients and modulate the host immune system.
  • Microorganisms contribute to gut ecosystem stability through antimicrobial activities.
  • Cooperative interactions among gut bacteria and with the host are vital for health.

Conclusions:

  • The gut microbiome is integral to human health and homeostasis.
  • Understanding microbial crosstalk is key to maintaining a stable and healthy gut ecosystem.
  • Probiotics and commensal bacteria engage in beneficial interactions with the host.