Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Genome sequencing reveals genes under selection for olfactory transduction in highland sheep.

Molecular genetics and genomics : MGG·2026

Same author

Multi-scale petrographic and geotechnical characterization of Kuldana formation limestone and implications for asphalt concrete stiffness and fatigue design.

Scientific reports·2026

Same author

Structurally engineered Co-CeO<sub>2</sub> dispersed on N-lemon biochar for efficient energy storage and water splitting.

RSC advances·2026

Same author

Seasonal Prevalence, Molecular Identification and Therapeutic Management of Enterotoxemia Caused by Clostridium perfringens Type D in Goats of Peshawar and Charsadda Districts, Pakistan.

Veterinary medicine and science·2026

Same author

The impact of reducing dialysate flows during haemodiafiltration and haemodialysis sessions.

Journal of nephrology·2026

Same author

Sulfonamide resistance as a global one health challenge.

The Journal of antibiotics·2026

Search research articles

Related Experiment Video

Updated: May 2, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Dialysate cytokine levels do not predict encapsulating peritoneal sclerosis.

Catriona Goodlad¹, Frederick W K Tam¹, Sohail Ahmad¹

¹Renal Section, Department of Medicine, Imperial College, London, United Kingdom; and Senior Statistician, Queen Mary University of London, London, United Kingdom.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis

|March 4, 2014

Summary

Dialysate cytokines like IL-6 and MCP-1 were higher in patients who developed encapsulating peritoneal sclerosis (EPS). However, these markers did not improve EPS prediction beyond established clinical factors in long-term peritoneal dialysis patients.

Keywords:

Cytokines encapsulating peritoneal sclerosis screening

More Related Videos

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage

Published on: April 28, 2022

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Related Experiment Videos

Last Updated: May 2, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage

A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage

Published on: April 28, 2022

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Area of Science:

Nephrology
Biomarkers
Peritoneal Dialysis Complications

Background:

Encapsulating peritoneal sclerosis (EPS) is a severe complication of long-term peritoneal dialysis (PD).
Predicting EPS onset is challenging, with known risk factors including PD duration, high glucose exposure, and reduced renal function.
This study explored dialysate cytokines as potential predictors of EPS.

Purpose of the Study:

To investigate if specific dialysate cytokines can predict the onset of encapsulating peritoneal sclerosis (EPS).
To compare the predictive value of dialysate cytokines against established clinical risk factors for EPS.

Main Methods:

Prospective collection of dialysate and clinical data from 151 PD patients (2003-2010).
Measurement of dialysate cytokine levels (MCP-1, CCL18, IL-6, CCL15, angiogenin) using ELISA.
Logistic regression analysis to assess cytokine predictive value for EPS development in 17 patients.

Main Results:

Elevated levels of dialysate IL-6, MCP-1, and CCL15 were observed in patients who later developed EPS.
A predictive model using these cytokines did not outperform a model based on clinical markers like PD duration and membrane transport status.

Conclusions:

While MCP-1, IL-6, and CCL15 are elevated in pre-EPS patients' dialysate, they do not enhance EPS prediction.
Current clinical risk factors remain the primary basis for predicting EPS in peritoneal dialysis patients.