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Post discharge growth assessment in preterm infants: implications of adopting the WHO standards
Carlos A Fustiñana1, Diana Rodríguez1, Gonzalo Mariani1
1Servicio de Neonatología, Hospital Italiano de Buenos Aires.
Insights
The World Health Organization (WHO) growth standards for preterm infants showed higher rates of growth retardation compared to the Sociedad Argentina de Pediatría (SAP) standards. However, changing growth assessment standards did not significantly alter clinical follow-up practices in the first year.
Area of Science:
- Pediatrics
- Neonatology
- Growth Monitoring
Background:
- The World Health Organization (WHO) growth standards have been the benchmark for assessing infant growth since 1986.
- Implementing WHO standards in Argentina could enhance the identification of suboptimal growth in preterm infants.
Purpose of the Study:
- To compare growth retardation rates in preterm infants (birth weight <1500g) using WHO and Sociedad Argentina de Pediatría (SAP) standards.
- To evaluate differences in weight, height, and head circumference assessments between the two standards.
Main Methods:
- A cohort study included 204 preterm infants with very low birth weight (VLBW).
- Anthropometric measurements (weight, height, head circumference) were taken at multiple postmenstrual weeks.
- Statistical analysis involved Z-scores, Student's t-test, and chi-squared test to compare WHO and SAP standards.
Main Results:
- The SAP standards indicated greater weight and height growth than WHO standards, particularly in males during the first year.
- Growth retardation in height was noted with WHO standards for both sexes.
- A significantly higher proportion of infants fell below -2 standard deviations for weight at 3 months using WHO standards (p < 0.01).
Conclusions:
- Adopting WHO growth standards did not necessitate significant changes in clinical follow-up practices for preterm infants in their first year.
- The study highlights subtle differences in growth assessment between WHO and SAP standards, particularly concerning weight in early infancy.
Introduction:
The WHO standards have been used as a gold standard for growth assessment in preterm infants since 1986. The introduction of the WHO standards in Argentina could improve detection of sub-optimal growth.
Objective:
To compare the proportion of growth retardation in terms of weight, body height and head circumference in preterm infants with a birth weight less than 1500 g (VLBW) assessed according to the WHO standards and the Sociedad Argentina de Pediatría (SAP) standards.
Population And Methods:
Cohort study in VLBW newborn infants. Measurements included were weight, height and head circumferences measured at 40, 53, 66, 79 and 92 postmenstrual weeks (±1 week). Sex was recorded as an independent outcome measure for both standards (WHO and SAP). Mean Z scores were analyzed for both standards using Student's test, and the difference of proportions was assessed using the c2 test (OR; 95% CI).
Results:
Two hundred and four infants were included. No differences were observed in anthropometric outcome measures at birth by sex. A greater growth was seen in terms of weight and height as per the SAP standards compared to the WHO standards, which was more marked in male infants than female infants, and which diminished around their first year of life. Growth retardation in terms of height was observed in both males and females assessed with the WHO standards. No differences were observed in head circumference. A higher proportion of patients with a weight below 2 standard deviations at 3 months old was found as per the WHO (p < 0.01; OR: 0.36; 95% CI: 0.150.78), but that was not the case with height and head circumference.
Conclusions:
This study allows to suggest that changing the standards does not imply a significant modification in our follow-up practice over the first year of life of an infant.
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