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Lemierre syndrome: not so forgotten!

Nishant Gupta1, Stephen M Kralovic, Dennis McGraw

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PubMed
Summary

Lemierre syndrome, a rare and dangerous illness, is caused by Fusobacterium necrophorum. Prompt diagnosis, potentially aided by bedside ultrasonography, is crucial for managing this severe septic thrombophlebitis.

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Area of Science:

  • Infectious Diseases
  • Vascular Surgery

Background:

  • Lemierre syndrome is a rare, life-threatening condition, often termed "the forgotten disease," with an incidence as low as 1 in a million.
  • It is typically caused by Fusobacterium necrophorum, originating in the pharynx and spreading via lymphatic vessels.

Observation:

  • This report details a case in a previously healthy 26-year-old man presenting with severe septic thrombophlebitis of the internal jugular vein.
  • The patient experienced a 2-week history of pharyngitis, complicated by challenging diagnostic factors including his presentation and travel history.

Findings:

  • The syndrome is characterized by rapid development of severe sepsis and septic thrombophlebitis of the internal jugular vein.
  • Diagnosis is frequently delayed, underscoring the need for timely identification.

Implications:

  • Bedside ultrasonography may significantly aid in the rapid diagnosis of Lemierre syndrome.
  • Early recognition and intervention are critical for improving patient outcomes in this severe illness.