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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
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Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
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Infection01:20

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
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Related Experiment Video

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Inducing Apical Periodontitis in Mice
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[Infection-related root resorption].

Andreas Filippi1

  • 1Universitätskliniken für Zahnmedizin der Universität Basel Klinik für zahnärztliche Chirurgie, Radiologie, Mundund Kieferheilkunde.

Swiss Dental Journal
|March 4, 2014
PubMed
Summary

Severe dental injuries like intrusion or avulsion can lead to infection-induced root resorption. This occurs when the pulp tears and the tooth

Area of Science:

  • Dentistry
  • Oral Biology
  • Pathology

Background:

  • Infection-induced root resorption is a complication following severe dental trauma.
  • Traumatic injuries such as intrusion and avulsion can disrupt the apical pulp and root surface.

Purpose of the Study:

  • To describe the pathological process of infection-induced root resorption.
  • To highlight the initial cellular and structural changes following traumatic dental injuries.

Main Methods:

  • Review of pathological mechanisms in dental trauma.
  • Analysis of histological changes in teeth with severe dislocation injuries.

Main Results:

  • Apical pulp tearing is a key event.
  • Significant cement defects and destruction of the cementoblast layer (precementum) are observed on the root surface.
Keywords:
Infektionsbedingte WurzelresorptionZahntraumaZementdefekt

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Conclusions:

  • Infection-induced root resorption is initiated by pulp damage and cementum defects after severe trauma.
  • The destruction of the precementum layer is a critical step in this process.