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Safety and long-term outcomes after percutaneous coronary intervention in patients with human immunodeficiency virus

Salem Badr1, Sa'ar Minha, Hironori Kitabata

  • 1Section of Interventional Cardiology, MedStar Heart Institute, MedStar Washington Hospital Center, Washington, District of Columbia.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|March 4, 2014
PubMed

Insights

Percutaneous coronary intervention (PCI) is safe for human immunodeficiency virus (HIV+) patients, showing similar long-term outcomes compared to HIV- individuals. Drug-eluting stents (DES) are recommended for HIV+ patients undergoing PCI.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Interventional Cardiology

Background:

  • Limited data exists on the risks associated with percutaneous coronary intervention (PCI) in patients with human immunodeficiency virus (HIV).
  • Understanding long-term outcomes of PCI in HIV-positive individuals is crucial for clinical management.

Purpose of the Study:

  • To evaluate the long-term clinical outcomes of PCI in patients with HIV.
  • To compare PCI outcomes between HIV-positive and HIV-negative patient groups.

Main Methods:

  • A case-control study comparing 112 HIV-positive patients with 112 matched HIV-negative controls who underwent PCI.
  • Data collected included baseline characteristics, procedural outcomes, and 2-year clinical outcomes.
  • Statistical analysis, including multivariable analysis, was used to identify correlates of major adverse cardiac events.

Main Results:

  • Baseline characteristics were similar, though HIV+ patients had higher rates of African American ethnicity and chronic renal insufficiency.
  • Major adverse cardiac events at 2 years were comparable between HIV+ and HIV- groups.
  • Chronic renal insufficiency and acute myocardial infarction were independent correlates of adverse outcomes. Drug-eluting stent (DES) use was beneficial in HIV+ patients.

Conclusions:

  • PCI is a safe procedure for HIV+ patients, achieving high success rates.
  • Long-term outcomes (2-year) after PCI are similar for HIV+ and HIV- patients.
  • Drug-eluting stents (DES) are recommended for HIV+ patients undergoing PCI.
Abstract

Keywords:
coronary artery diseasehuman immunodeficiency viruspercutaneous coronary intervention

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