Anomalous aortic origin of coronary arteries: 'anatomical' surgical repair
Régis Gaudin1, Olivier Raisky, Pascal R Vouhé
1Department of Pediatric Cardiac Surgery, Sick Children Hospital, University Paris Descartes, Sorbonne Paris Cité, Paris, France.
Insights
Anomalous aortic origin of coronary arteries is a rare defect with high sudden cardiac death risk. Anatomical repair is favored for high-risk cases, especially in young, active patients.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Cardiac Surgery
Background:
- Anomalous aortic origin of coronary arteries (AAOCA) is a rare congenital defect.
- AAOCA carries a significant risk of sudden cardiac death, particularly with specific anatomical features like an intramural course.
- Existing surgical techniques vary, including bypass grafting and unroofing procedures.
Purpose of the Study:
- To review the risks associated with anomalous aortic origin of coronary arteries.
- To discuss current and favored surgical repair strategies.
- To provide recommendations for surgical correction in symptomatic and asymptomatic patients.
Main Methods:
- Review of existing literature on anomalous aortic origin of coronary arteries.
- Discussion of surgical techniques, including coronary artery bypass grafting, pulmonary artery translocation, unroofing, and patch enlargement.
- Emphasis on 'anatomical' repair involving neo-ostium creation and elimination of intramural segments.
- Consideration of coronary artery reimplantation for specific variants.
Main Results:
- High-risk features for sudden cardiac death include interarterial course with intramural segments, hypoplasia/stenosis, or abnormal orifice.
- 'Anatomical' repair is favored for its effectiveness in creating a normal coronary ostium and take-off angle.
- Reimplantation may be suitable for AAOCA variants lacking an intramural course.
Conclusions:
- Surgical correction is essential for symptomatic patients and asymptomatic individuals with myocardial ischemia.
- High-risk asymptomatic variants, particularly anomalous left coronary artery with intramural course in young active individuals, warrant surgical intervention.
- Anatomical repair offers a preferred approach to mitigate risks associated with AAOCA.
Abstract:
Anomalous aortic origin of coronary arteries (left coronary from right sinus or right coronary from left sinus) is a rare congenital defect, which carries a high risk of sudden cardiac death. The risk is particularly high when the interarterial course between the great arteries has an intramural segment, or is hypoplastic/stenotic, or has an abnormal orifice. Various surgical techniques have been used, including coronary artery bypass grafting, pulmonary artery translocation, partial or complete unroofing of the intramural course and patch enlargement of the interarterial course. We favour 'anatomical' repair that creates an enlarged neo-ostium into the appropriate sinus, eliminates completely the intramural segment and restores a normal angle of take-off. Reimplantation of the anomalous coronary artery may be indicated in variants without an intramural course. Surgical correction is mandatory for symptomatic and asymptomatic patients with evidence of myocardial ischaemia under stress; it is recommended in asymptomatic patients with high-risk variants (anomalous left coronary artery with the intramural course), particularly in young patients with strenuous activities.
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