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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Kidney Structure01:45

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The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
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Chronic Kidney Disease III: Interprofessional Care01:28

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Related Experiment Video

Updated: May 2, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
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Kidney cancer, version 2.2014.

Robert J Motzer1, Eric Jonasch, Neeraj Agarwal

  • 1From 1Memorial Sloan-Kettering Cancer Center; 2The University of Texas MD Anderson Cancer Center; 3Huntsman Cancer Institute at the University of Utah; 4Dana-Farber/Brigham and Women's Cancer Center; 5Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; 6University of Alabama at Birmingham Comprehensive Cancer Center; 7Vanderbilt-Ingram Cancer Center; 8UC San Diego Moores Cancer Center; 9Moffitt Cancer Center; 10Stanford Cancer Institute; 11The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; 12Robert H. Lurie Comprehensive Cancer Center of Northwestern University; 13University of Colorado Cancer Center; 14City of Hope Comprehensive Cancer Center; 15Roswell Park Cancer Institute; 16Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance; 17Massachusetts General Hospital Cancer Center 18The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; 19Fox Chase Cancer Center; 20Duke Cancer Institute; 21University of Michigan Comprehensive Cancer Center; 22UCSF Helen Diller Family Comprehensive Cancer Center; 23St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; 24Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; and 25National Comprehensive Cancer Network.

Journal of the National Comprehensive Cancer Network : JNCCN
|March 4, 2014
PubMed
Summary
This summary is machine-generated.

This summary covers 2014 NCCN Guidelines for advanced non-clear cell kidney cancer. It details updated treatment recommendations for oncologists managing these complex cases.

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Area of Science:

  • Oncology
  • Nephrology
  • Clinical Practice Guidelines

Background:

  • Advanced non-clear cell kidney cancer presents unique management challenges.
  • The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer care.
  • Regular guideline updates are crucial for incorporating new research and treatment options.

Purpose of the Study:

  • To summarize key updates in the 2014 NCCN Guidelines for Kidney Cancer.
  • To focus on treatment recommendations for advanced non-clear cell carcinoma.
  • To provide clinicians with accessible insights into current management strategies.

Main Methods:

  • Review of the 2014 NCCN Clinical Practice Guidelines in Oncology for Kidney Cancer.
  • Identification of specific recommendations for advanced non-clear cell histology.
  • Synthesis of information for clinical practice insights.

Main Results:

  • The 2014 guidelines include updated treatment recommendations for advanced non-clear cell kidney cancer.
  • These insights highlight specific management strategies relevant to this patient population.
  • The document serves as a focused summary of guideline content.

Conclusions:

  • Clinicians should consult the 2014 NCCN Guidelines for current treatment approaches.
  • Management of advanced non-clear cell kidney cancer benefits from adherence to updated guidelines.
  • These insights facilitate the practical application of NCCN recommendations.