Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

7.1K
The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
7.1K
Dose-Response Relationship: Overview01:03

Dose-Response Relationship: Overview

5.2K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
5.2K
Response Surface Methodology01:16

Response Surface Methodology

904
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
904
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

5.6K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
5.6K
Stringent Response in E. coli01:23

Stringent Response in E. coli

528
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
528
Reaction Rate02:53

Reaction Rate

51.4K
The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure.
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
51.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of fertility-sparing surgery and further prognostic factors in borderline tumors of the ovary.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2025
Same author

Impact of metformin, statins, and beta blockers on survival in patients with primary ovarian cancer: combined analysis of four prospective trials of AGO-OVAR and ENGOT/GCIG collaborators.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2025
Same author

Impact of lymphadenectomy rates in the quality assurance program in early ovarian cancer of the AGO Study Group - Real-world observations.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

Risk factors for anastomotic leakage and its impact on survival outcomes in radical multivisceral surgery for advanced ovarian cancer: an AGO-OVAR.OP3/LION exploratory analysis.

International journal of surgery (London, England)·2025
Same author

Impact of metformin, statins, and beta blockers on survival in patients with primary ovarian cancer: combined analysis of four prospective trials of AGO-OVAR and ENGOT/GCIG collaborators.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2024
Same author

Impact of adjuvant therapy on oncologic outcomes in uterine-confined clear cell carcinoma of the endometrium.

Gynecologic oncology·2024
Same journal

Cluster randomized controlled trial of decision support for breast cancer chemoprevention, MiCHOICE.

Journal of the National Cancer Institute·2026
Same journal

Beyond R2: Assessing quality of trial level surrogate endpoints in colorectal cancer.

Journal of the National Cancer Institute·2026
Same journal

A novel classification of small bowel adenocarcinoma based on the hidden genome classifier: a multi-institutional study.

Journal of the National Cancer Institute·2026
Same journal

Response to Yu, Wang and Ge.

Journal of the National Cancer Institute·2026
Same journal

Re: Cardiovascular disease risk after radiotherapy and anthracycline-based chemotherapy for diffuse large B-cell lymphoma.

Journal of the National Cancer Institute·2026
Same journal

Welcome reduction of US cervical cancer rates despite state differences.

Journal of the National Cancer Institute·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

7.6K

Response

Volker Moebus1, Christian Jackisch, Andreas Schneeweiss

  • 1Affiliations of authors: Department of Gynecology and Obstetrics, Klinikum Frankfurt Höchst, Frankfurt, Germany (VM); Department of Gynecology and Obstetrics, Klinikum Offenbach GmbH, Offenbach, Germany (CJ); National Center for Tumor Diseases, University of Heidelberg, Heidelberg, Germany (AS); Department of Gynecology and Obstetrics, University of Duesseldorf, Duesseldorf, Germany (JH); Gynäkologisch-Onkologische Praxis Hannover, Hannover, Germany (H-JL); Department of Gynecology and Gynecologic Oncology, KEM Hussenstift, Essen, Germany (AdB); Department of Gynecology, University of Halle, Halle (Saale), Germany (CT); Medizinisches Zentrum Bonn-Friedensplatz, Bonn, Germany (CK); Department of Gynecology and Obstetrics, University of Bonn, Bonn, Germany (WK); Ev. Krankenhaus Bethesda, Brustzentrum Niederrhein, Mönchengladbach, Germany (UAN); Department of Gynecology and Obstetrics, University of Jena, Jena, Germany (IBR); WiSP Research Institute, Langenfeld, Germany (AH); Department of Gynecology and Obstetrics, University of Ulm, Ulm, Germany (RK); Department of Gynecology and Obstetrics, Helios Klinikum Berlin-Buch, Berlin, Germany (MU).

Journal of the National Cancer Institute
|March 4, 2014
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.3K
Proboscis Extension Response PER Assay in Drosophila
23:42

Proboscis Extension Response PER Assay in Drosophila

Published on: April 29, 2007

30.3K

Related Experiment Videos

Last Updated: May 2, 2026

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

7.6K
Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm
12:12

Irrelevant Stimuli and Action Control: Analyzing the Influence of Ignored Stimuli via the Distractor-Response Binding Paradigm

Published on: May 14, 2014

10.3K
Proboscis Extension Response PER Assay in Drosophila
23:42

Proboscis Extension Response PER Assay in Drosophila

Published on: April 29, 2007

30.3K