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Macular serpiginous choroiditis.

A M Mansour1, L M Jampol, K H Packo

  • 1Department of Ophthalmology, Northwestern University Medical School, Chicago, IL.

Retina (Philadelphia, Pa.)
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

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Serpiginous choroiditis can originate in the macula, often leading to poor vision and subretinal neovascularization. Initial fluorescein angiography may mimic choroidal ischemia due to opaque retinal pigment epithelium.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Serpiginous choroiditis is an inflammatory condition affecting the choroid.
  • Typical presentation involves peripapillary activity.
  • Macular involvement can alter the typical presentation and prognosis.

Observation:

  • Seven eyes from four patients presented with serpiginous choroiditis originating in the macula.
  • No initial peripapillary activity was observed in these cases.
  • Subretinal neovascularization was a noted complication.

Findings:

  • Acute lesions on fluorescein angiography showed hypofluorescence, initially suggesting choroidal ischemia.
  • In one case, fluorescein angiography indicated that hypofluorescence may be due to blocked fluorescence from opaque retinal pigment epithelium.

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  • Macular serpiginous choroiditis was associated with a poor visual prognosis.

    • Implications:

    • This atypical presentation of serpiginous choroiditis requires careful diagnostic consideration.
    • Understanding the role of retinal pigment epithelium in fluorescein angiography findings is crucial for accurate diagnosis.
    • Early recognition and management may be vital for patients with macular serpiginous choroiditis to improve visual outcomes.