Related Experiment Video
Updated: May 2, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
The role of capsule endoscopy in acute gastrointestinal bleeding
1Department of Gastroenterology, Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Insights
Capsule endoscopy aids in diagnosing obscure gastrointestinal (GI) bleeding when standard tests fail. This review examines its effectiveness for upper GI tract and small bowel bleeding sources.
Area of Science:
- Gastroenterology
- Medical Imaging
Background:
- Acute gastrointestinal (GI) bleeding causes significant hospitalizations (400,000 annually) with a 5-10% mortality rate.
- Approximately 5% of acute GI bleeding cases remain undiagnosed after standard esophagogastroduodenoscopy and ileocolonoscopy.
Purpose of the Study:
- To review the role and effectiveness of capsule endoscopy in evaluating patients with acute GI bleeding.
- To assess capsule endoscopy's sensitivity and outcomes in detecting bleeding sources in the upper GI tract and small bowel.
Main Methods:
- Review of recent studies on capsule endoscopy in acute GI bleeding.
- Analysis of capsule endoscopy's diagnostic performance compared to standard procedures.
Main Results:
- Capsule endoscopy is a state-of-the-art tool for inspecting the entire small bowel.
- It demonstrates high sensitivity in detecting causes of obscure GI bleeding.
Conclusions:
- Capsule endoscopy is crucial for diagnosing obscure GI bleeding.
- It offers a comprehensive evaluation for bleeding originating from the upper GI tract or small bowel.
Abstract:
Acute gastrointestinal (GI) bleeding is a common cause of hospitalization, resulting in about 400,000 hospital admissions annually, with a mortality rate of 5-10%. It is estimated that 5% of acute GI bleedings are of obscure origin with a normal esophagogastroduodenoscopy and ileocolonoscopy. Capsule endoscopy is the state-of-the-art procedure for inspection of the entire small bowel with a high sensitivity for the detection of causes of bleeding. In recent years, many studies have addressed the sensitivity and outcome of capsule-endoscopy procedures in patients with acute GI bleeding. This review looks at the role of capsule endoscopy in the evaluation of patients with acute GI bleeding from either the upper GI tract or small bowel.
Related Concept Videos
Endoscopic Procedures III: Video Capsule Endoscopy
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Endoscopic Procedures V: ERCP
Patient...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
