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Updated: May 2, 2026

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

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Therapeutic strategies to alter the oxygen affinity of sickle hemoglobin

Martin K Safo1, Gregory J Kato2

  • 1Department of Medicinal Chemistry, Institute for Structural Biology and Drug Discovery, School of Pharmacy, Virginia Commonwealth University, 800 E. Leigh Street, P.O. Box 980540, Richmond, VA 23219-1540, USA.

Hematology/Oncology Clinics of North America
|March 5, 2014
PubMed

Keywords:
5-HMFAntisicklingHemoglobin allosteric effectorsR stateSickle cell

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