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Influence of beta-sitosterol on the fibrinolytic potential in rabbits
1Institute of Pharmacology and Toxicology, Medical Academy Erfurt, GDR.
Abstract:
Long-term treatment of rabbits with beta-sitosterol (40 mg/kg over 3 months) caused an increased fibrinolytic activity in blood, an increased fibrinolytic capacity and an enhanced plasminogen activator activity in tissue of lungs and kidneys. The 3-months lasting beta-sitosterol administration did not influence the content of plasminogen activator inhibitor, plasminogen, alpha 2-antiplasmin, antithrombin III and fibrinogen.