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Quality control of 125I-labelled fibrinogen of various species
M Richter1, U Cyranka, P Walsmann
1Institute of Pharmacology and Toxicology, Medical Academy, Erfurt, GDR.
Abstract:
The modified chloramine-T method used for radioiodination of human, rat, and bovine fibrinogen guaranteed mild labelling conditions and a satisfactory labelling efficiency. The quality of the 125I-human, rat, and bovine fibrinogen preparations obtained met the requirements with respect to clottability, low content of 125Iodide as well as in vitro and in vivo stability.