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Communicating the parameter uncertainty in the IQWiG efficiency frontier to decision-makers
Björn Stollenwerk1, Stefan K Lhachimi, Andrew Briggs
1Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Health Economics and Health Care Management, Neuherberg, Germany.
Health Economics
|March 5, 2014
Summary
This study evaluates tools for assessing uncertainty in Germany's health economic efficiency frontier (EF) approach. It proposes new methods for clearer communication of price reimbursement uncertainty.
Area of Science:
- Health Economics
- Health Technology Assessment
Background:
- The Institute for Quality and Efficiency in Health Care (IQWiG) developed the efficiency frontier (EF) approach for economic evaluations in Germany's statutory health insurance system.
- The EF approach presents unique challenges for assessing and communicating parameter uncertainty compared to traditional methods.
Purpose of the Study:
- To evaluate established tools for assessing and communicating parameter uncertainty within the IQWiG EF approach.
- To propose modifications and new methods for improved interpretation of uncertainty in health economic evaluations.
Main Methods:
- Review and assessment of established graphical tools (scatter plots, confidence bands, contour plots) for displaying uncertainty.
- Evaluation of methods for communicating uncertainty related to reimbursable prices.
- Proposal of price reimbursement acceptability curves as a modification of cost-effectiveness acceptability curves.
Main Results:
- Many established graphical tools are difficult to interpret within the EF approach.
- Net monetary benefit offers an intuitive way to interpret parameter uncertainty.
- Price reimbursement acceptability curves are proposed for clearer communication of price uncertainty.
Conclusions:
- This research addresses a gap in handling uncertainty within the IQWiG EF approach for economic evaluations.
- Further definition is needed regarding the precise impact of uncertainty on price determination.
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