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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma I: Introduction01:28

Asthma I: Introduction

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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

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Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

4.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Asthma in pregnancy: a hit for two.

Vanessa E Murphy1, Michael Schatz

  • 1Centre for Asthma and Respiratory Diseases, University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia. 2 Dept of Allergy, Kaiser Permanente Medical Center, San Diego, CA, USA.

European Respiratory Review : an Official Journal of the European Respiratory Society
|March 5, 2014
PubMed
Summary
This summary is machine-generated.

Pregnant individuals with asthma face increased risks for adverse birth outcomes, including low birth weight and preterm birth. However, active asthma management and appropriate medication use can mitigate these risks for both mother and child.

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Murine Model of Allergen Induced Asthma
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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
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Murine Model of Allergen Induced Asthma
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Area of Science:

  • Obstetrics and Gynecology
  • Pulmonology
  • Neonatology

Background:

  • Asthma affects a significant number of pregnant individuals.
  • Pregnancy can exacerbate asthma symptoms and increase risks for adverse perinatal outcomes.
  • Understanding the impact of asthma on pregnancy is crucial for maternal and infant health.

Purpose of the Study:

  • To review current data on risks associated with asthma during pregnancy.
  • To evaluate the safety and efficacy of asthma management strategies and medications in pregnant individuals.
  • To identify factors influencing asthma control and perinatal outcomes.

Main Methods:

  • Literature review of recent studies on asthma in pregnancy.
  • Analysis of data on perinatal outcomes, including birth weight, gestational age, and congenital malformations.
  • Examination of the role of asthma exacerbations, viral infections, and medication adherence.

Main Results:

  • Increased risks of low birth weight, small for gestational age, and preterm birth, particularly with moderate-to-severe asthma and exacerbations.
  • A small but significant increased risk of congenital malformations (e.g., cleft lip) and neonatal hospitalisation/death.
  • Asthma medication use in pregnancy is generally considered safe, with benefits outweighing risks.
  • Viral infections are key triggers for asthma exacerbations, potentially linked to immunological changes.

Conclusions:

  • Active asthma management, including appropriate medication, is vital to reduce perinatal risks.
  • Addressing poor medication adherence is essential for improving asthma control during pregnancy.
  • Optimizing asthma care in pregnancy benefits both maternal and infant health outcomes.