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General evaluation of periventricular-intraventricular hemorrhage in premature infants in mainland China
Jing Liu1, Li-Wen Chang2, Qi Wang3
1Department of Neonatology & Nicu, Bayi Children's Hospital Affiliated With Beijing Military Region General Hospital, Beijing, China.
Insights
Premature infants in China have a high incidence of periventricular-intraventricular hemorrhage (PIVH). Key risk factors include low gestational age, low birth weight, and ventilatory treatment, suggesting a 2000g screening cutoff.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
- Medical Imaging
Background:
- Periventricular-intraventricular hemorrhage (PIVH) is a significant concern in premature infants.
- Understanding PIVH incidence and risk factors in specific populations is crucial for targeted interventions.
Purpose of the Study:
- To determine the incidence of PIVH in premature infants in mainland China.
- To identify high-risk factors associated with PIVH in this population.
Main Methods:
- A cohort of 1122 premature infants (<37 weeks gestation) was studied.
- Intracranial ultrasound examinations were performed within one week of birth.
- Perinatal data were collected to analyze risk factors for PIVH.
Main Results:
- The incidence of PIVH was 55.2% among premature infants in mainland China.
- Mild PIVH accounted for 82.2% of cases, while severe PIVH was 17.8%.
- Significant risk factors included low gestational age, low birth weight, low Apgar score, and ventilatory treatment.
Conclusions:
- Multiple high-risk factors contribute to PIVH in premature infants.
- A birth weight screening cutoff of 2000g is suggested as more appropriate for China to identify at-risk infants.
Objective:
To explore the incidence and analyze the high risk factors of PIVH in premature infants in mainland China.
Materials And Methods:
A total of 1122 premature infants at <37 weeks gestation were enrolled in this study. All the infants received intracranial ultrasound examinations within 1 week after birth, and the perinatal data were recorded to analyze the high risk factors for PIVH.
Results:
The results showed that the incidence rate of PIVH was 55.2% in mainland Chinese population. Among these cases, mild degrees of PIVH accounted for 82.2% and severe degrees of PIVH accounted for only 17.8%. The most important risk factors related to PIVH were low gestational age, low birth weight, low Apgar score and ventilatory treatment, etc.
Conclusions:
It suggested that there were many high risk factors related to PIVH in premature infants and a screening cutoff point of 2000 g appeared to be more adequate for China.
