Thyroid dysfunction in hyperemesis gravidarum: a study in Turkish pregnant women

In this study we investigate the possible relation of thyroid dysfunction and thyroid antibodies to hyperemesis gravidarum.

Thirty-seven patients with hyperemesis gravidarum and 33 healthy controls have been included in this study.

Thyroid dysfunction was significantly more common than in controls (38% vs 6%, p=0.002). Thyroglobulin antibodies were also significantly more common in patients with hyperemesis gravidarum than controls (54 IU/mL vs. 14 IU/mL, p=0.03).

Hyperemesis gravidarum can be a risk factor for postpartum thyroid dysfunction. Thyroid antibodies must be checked in the hyperemesis population in an endemic goitre region and/or iodine replacement regions.