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Updated: May 2, 2026

Isolation of Lymphocytes from Mouse Genital Tract Mucosa
Published on: September 3, 2012
Role of the innate immunity in female reproductive tract
Fatemehsadat Amjadi1, Ensieh Salehi2, Mehdi Mehdizadeh3
1Applied Physiology Research Center and Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran ; Department of Anatomy, Tehran University of Medical Science, Tehran, Iran.
Abstract:
The mucosal immune system in the female reproductive tract (FRT) is well equipped to meet the sexually transmitted pathogens, allogeneic sperm, and the immunologically distinct fetus. Analysis of the FRT indicates that epithelial cells provide a physical barrier against pathogens and microbial infections as well as secretions containing anti-microbial peptides, cytokines, and chemokines which recruit and activate immune cells. Epithelial and immune cells confer protection in part through Toll-like receptors. The aim of this literature is to review the diverse components of the innate immune system, contributing to an exclusive protection system throughout the FRT.
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