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Updated: Aug 15, 2026

10:02
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
The effect of iloprost on the rabbit eye
R A Moses1, D W Schmoll, B Dihenia
1Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri.
Abstract:
Some prostaglandins, topically applied, are known to lower intraocular pressure; a few have been shown to increase facility of outflow. Iloprost (ZK36374), a stable PGI2 analog, was tested in rabbits for effect on intraocular pressure and facility, but was found totally inactive on either.

