Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

2.7K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
2.7K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

2.6K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.6K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

482
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
482
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

929
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
929
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

415
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
415
Drug toxicity: Idiosyncratic Reactions01:16

Drug toxicity: Idiosyncratic Reactions

220
Idiosyncratic drug reactions represent abnormal chemical responses that vary significantly among individuals, ranging from extreme sensitivity to low doses to insensitivity to high doses. These reactions often occur due to the drug's covalent binding with serum proteins, forming a foreign hapten that triggers an immunotoxicological response. The variability in drug reactions has a strong pharmacogenetic foundation, with genetic differences crucial in how individuals metabolize drugs. For...
220

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Access to general practice: why policy must be rural-proofed.

The British journal of general practice : the journal of the Royal College of General Practitioners·2026
Same author

Creating equitable pathways to close the gap in dermatology workforce representation and skin health for Indigenous Australians.

The Journal of investigative dermatology·2026
Same author

Tissue microbiology of 310 surgically deroofed hidradenitis suppurativa lesions.

Journal of the American Academy of Dermatology·2026
Same author

Culturally Safe and Decentralised Care: Patient Experiences of a Dermatology Clinic Embedded in an Aboriginal and Torres Strait Islander Primary Health Care Service.

The Australasian journal of dermatology·2026
Same author

Insight into the role of 3D reconstruction of MRI imaging for complex anogenital hidradenitis suppurativa: A single-center case series.

JPRAS open·2026
Same author

A 10-Year Retrospective Cohort Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital.

The Australasian journal of dermatology·2026
Same journal

Revisiting the Role of Antibiotics in Hidradenitis Suppurativa in the Biologic Era.

The Australasian journal of dermatology·2026
Same journal

Benzalkonium Chloride in Eye Drops Causing Allergic Contact Dermatitis: A Case Series.

The Australasian journal of dermatology·2026
Same journal

The Dermatologist's Role in Early PMOS Diagnosis.

The Australasian journal of dermatology·2026
Same journal

From Curriculum Variation to Clinical Capability: Advancing Dermatology Education in Australia.

The Australasian journal of dermatology·2026
Same journal

Fatal Phenobarbital-Associated Toxic Epidermal Necrolysis With Severe Acute Kidney Injury and Multiorgan Failure: Prognostic Value of SCORTEN and ALDEN.

The Australasian journal of dermatology·2026
Same journal

Granulomatous Vasculitis: An Unusual Manifestation of Metastatic Crohn's Disease.

The Australasian journal of dermatology·2026
See all related articles

Related Experiment Video

Updated: May 2, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

15.4K

Warfarin-induced erythroderma.

Casey J Rowe1, Ivan Robertson, Daniel James

  • 1Department of Dermatology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; University of Queensland Centre for Clinical Research, Herston, Queensland, Australia.

The Australasian Journal of Dermatology
|March 6, 2014
PubMed
Summary
This summary is machine-generated.

Erythroderma, a severe skin condition, can be triggered by medications. This case highlights a rare instance of erythroderma caused by warfarin, a common anticoagulant.

Keywords:
drug reactionerythrodermawarfarin

More Related Videos

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients
04:56

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients

Published on: August 4, 2023

1.4K
Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

19.9K

Related Experiment Videos

Last Updated: May 2, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

15.4K
Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients
04:56

Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients

Published on: August 4, 2023

1.4K
Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

19.9K

Area of Science:

  • Dermatology
  • Pharmacology
  • Internal Medicine

Background:

  • Erythroderma is a critical dermatological condition with diverse causes.
  • Drug reactions are a significant etiology, with carbamazepine, penicillin, and allopurinol frequently implicated.
  • Identifying novel drug-induced erythroderma is crucial for patient safety.

Observation:

  • A 78-year-old female patient presented with erythroderma.
  • The patient was undergoing treatment with warfarin, a widely used anticoagulant.
  • The clinical presentation was unique and suggestive of an unusual drug reaction.

Findings:

  • Warfarin was identified as the causative agent for the patient's erythroderma.
  • This represents a rare and previously undocumented adverse reaction to warfarin.
  • The diagnosis was confirmed through clinical observation and exclusion of other etiologies.

Implications:

  • This case expands the known spectrum of drug-induced erythroderma.
  • Clinicians should consider warfarin as a potential cause of erythroderma, especially in patients on anticoagulation therapy.
  • Further research may be warranted to understand the mechanism of warfarin-induced erythroderma.