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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Acyclic nucleoside phosphonates: a study on cytochrome P450 gene expression

Jana Nekvindova1, Juan Antonio Contreras, Peter Juvan

  • 1Faculty of Medicine and Dentistry, Institute for Molecular and Translational Medicine, Palacky University , Olomouc , Czech Republic .

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|March 6, 2014
PubMed
Summary

Adefovir dipivoxil (AD) and tenofovir disoproxil (TD) are antiviral drugs. Studies show these nucleotide analogues do not significantly induce cytochrome P450 enzymes, suggesting a low risk of drug-drug interactions.

Keywords:
AdefovirCYPPMEAPMPAantiviraldrug metabolisminductiontenofovir

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