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Updated: May 2, 2026

07:16
Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis
Published on: December 30, 2025
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Thrombosed dural sinus malformation in a fetus: a case report
Hiroko Asai1, Toshio Okamoto1, Etsushi Tsuchida1
1Asahikawa Medical University, Departmemt of Pediatrics, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Hokkaido, Japan.
Summary
A rare thrombosed dural sinus malformation (DSM) in a fetus presented with a posterior fossa mass. Despite initial concerns, the infant experienced normal neurological development, highlighting the need for improved diagnostic accuracy.
Area of Science:
- Neuroscience
- Developmental Biology
- Medical Imaging
Background:
- Thrombosed dural sinus malformation (DSM) is a rare condition with incompletely characterized clinical features.
- This study details the clinical course of a patient with a thrombosed DSM and reviews live birth outcomes from existing literature.
Observation:
- Fetal ultrasonography at 25 weeks gestation revealed a posterior fossa mass.
- The intracranial mass size stabilized then decreased from 33 weeks gestation.
- Postnatal diagnosis confirmed dural sinus thrombosis via MRI and venography; no hydrocephalus or brain damage was observed.
Findings:
- The infant presented with an enlarged head circumference at birth (+2.0 SD, 35.6 cm).
- Despite the enlarged circumference, the infant exhibited normal neurological outcomes at 1 year of age.
- This contrasts with the reported necessity of normal cranial circumference for favorable prognosis.
Implications:
- Accurate prenatal diagnosis of thrombosed DSM is crucial for appropriate counseling.
- Further research is needed to enhance diagnostic accuracy for this rare fetal anomaly.
- Favorable neurological outcomes are possible even with deviations in cranial circumference.
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