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Updated: May 2, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
[Guideline 'Gastroesophageal reflux disease in children from 0-18 years']
Marc A Benninga1, Marjolein Y Berger, Leonie M A J Venmans
1Academisch Medisch Centrum (AMC), afd. Kindergeneeskunde, Amsterdam.
Insights
A new guideline for pediatric gastroesophageal reflux disease (GERD) emphasizes diagnosis through history and physical exams. It clarifies that GERD is distinct from physiological reflux, advising against overuse of medication, especially in infants.
Area of Science:
- Pediatric Gastroenterology
- Clinical Practice Guidelines
Background:
- Gastroesophageal reflux is common in children, but distinguishing it from gastroesophageal reflux disease (GERD) is crucial.
- Previous guidelines from NASPGHAN and ESPGHAN informed the development of this new Dutch guideline.
Purpose of the Study:
- To provide a multidisciplinary guideline for managing GERD in children aged 0-18 years.
- To clarify the distinction between physiological gastroesophageal reflux and GERD.
- To guide appropriate treatment decisions for pediatric GERD.
Main Methods:
- Development of a multidisciplinary guideline based on existing international guidelines (NASPGHAN, ESPGHAN).
- Emphasis on clinical assessment, including history and physical examination, for diagnosis.
- Establishment of a therapeutic action plan for confirmed GERD cases.
Main Results:
- History and physical examination are typically sufficient for diagnosing GERD in children.
- A clear distinction is made between physiological reflux and GERD.
- Over-prescription of medications, particularly for infants, is noted as a practical issue.
Conclusions:
- The guideline aims to improve the diagnosis and management of GERD in children.
- It advocates for a more conservative approach, reserving medication for diagnosed GERD.
- Accurate differentiation between reflux and GERD is key to appropriate therapeutic interventions.
Abstract:
In 2102, a multidiscplinary guideline was developed on behalf of the Dutch Association of Pediatrics entitled 'Gastroesophageal reflux disease in children from 0-18 years'. The North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guideline from 2009 served for guidance. History and physical examination are usually sufficient for diagnosing gastroesophageal reflux disease. It is important to make a distinction between gastroesophageal reflux, a physiological phenomenon in children, and gastroesophageal reflux disease. In practice, medications are provided too often, especially in infants. Only children suffering from gastroesophageal reflux disease should be treated according to the therapeutical action plan.
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