Related Experiment Video
Updated: Apr 30, 2026
04:40
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
14.9K
Non-coronary atherosclerosis
Augusto Gallino1, Victor Aboyans, Curt Diehm
1Division of Vascular Medicine, Ospedale San Giovanni, 6500 Bellinzona, Switzerland.
European Heart Journal
|March 6, 2014
Summary
Atherosclerosis often affects arteries beyond the heart, particularly in the lower extremities. Increased awareness and an interdisciplinary approach are crucial for managing this multifocal disease and its prognostic implications.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
Background:
- Clinical focus on atherosclerosis has historically centered on coronary arteries.
- Recent guidelines and registries highlight peripheral artery disease and multifocal atherosclerosis.
- Awareness of non-coronary atherosclerosis and its prognostic impact remains low.
Purpose of the Study:
- To enhance awareness of non-coronary atherosclerosis and its clinical significance.
- To emphasize the importance of atherosclerosis involvement across different arterial territories.
- To propose recommendations for managing multifocal atherosclerosis.
Main Methods:
- Review of current literature and guidelines on peripheral artery disease.
- Analysis of the clinical presentation, diagnosis, and co-existence of atherosclerosis in distinct arterial territories.
- Synthesis of expert opinion from an ESC Working Group meeting.
Main Results:
- Atherosclerosis is a widespread disease affecting multiple arterial beds, not just the coronary arteries.
- Non-coronary atherosclerosis, especially in lower extremities, carries significant prognostic implications.
- An interdisciplinary approach is essential for comprehensive management.
Conclusions:
- Elevating awareness of non-coronary atherosclerosis is critical for the medical community and public.
- Integrated management strategies are needed to address the complexity of multifocal atherosclerosis.
- Further research and clinical guidelines are necessary to improve patient outcomes.
More Related Videos
Related Concept Videos
01:30Coronary Artery Disease I: Introduction
1.8K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.8K
01:26Coronary Artery Disease II: Pathophysiology
1.1K
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
1.1K
01:30Coronary Artery Disease III: Clinical Manifestations
620
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
620
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
943
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
943
01:30Atherosclerosis I: Introduction
2.5K
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
2.5K
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
948
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
948