Related Experiment Video
Updated: May 2, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
In vitro determination of aceclofenac Mouth Dissolving Tablets
Shobhit Shobhit1, Satish Kumar Gupta1
1Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India.
Abstract:
In the present study, Mouth Dissolving Tablets (MDTs) of aceclofenac were formulated by direct compression technique. Sodium starch glycolate and crospovidone were employed as superdisintegrants in various concentrations like 2%, 3% and 4% w/w. All prepared tablets were evaluated for weight variation, hardness, drug content, friability, disintegration time, in vitro wetting time and percent drug release. MDTs containing 4% w/w concentration of crospovidone give best results and is therefore considered as the best formula. It has shown 30 s disintegration time, 25 s wetting time and 79.34% in vitro release of drug in 25 min.
Related Concept Videos
In Vitro Drug Dissolution: Alternative Methods
In Vitro Drug Dissolution: Compendial Testing Models I
In Vitro Drug Dissolution: Compendial Testing Models II
Methods for Studying Drug Absorption: In vitro
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
Drug Product Performance: In Vitro–In Vivo Correlation
In Vitro Drug Release Testing: Overview, Development and Validation

