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Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures
Published on: November 14, 2025
Like a slippery fish, a little slime is a good thing: the glycocalyx revealed
1Virginia Commonwealth University Medical Center, Richmond, VA, USA. cbiddle@hsc.vcu.edu
Abstract:
The glycocalyx is a dynamic network of multiple membrane-bound complexes lining the vascular endothelium. Its role in maintaining vascular homeostasis includes regulating vascular permeability as well as a range of vital functions, such as mechanotransduction, hemostasis, modulation of inflammatory processes, and serving as an antiatherogenic. Revisionist thinking about the Starling principle is discussed in terms of the major influence of the glycocalyx on capillary and tissue fluid homeostasis. The clinical and pathophysiologic threats to the glycocalyx are reviewed as well as strategies to maintain its integrity.
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