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Related Experiment Video

Updated: May 2, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

Placenta accreta: conservative approach.

G Di Luigi¹, F Patacchiola², L Di Stefano²

¹Department of Obstetrics and Gynecology, University of L 'Aquila, Italy. giandiluigi@hotmail.com

Clinical and Experimental Obstetrics & Gynecology

|March 7, 2014

Summary

This summary is machine-generated.

Placenta accreta, an abnormally invasive placental implantation, can cause severe hemorrhage. This case highlights conservative management including uterine artery embolization and methotrexate for a patient with uterine fibroids desiring future fertility.

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Area of Science:

Obstetrics and Gynecology
Reproductive Medicine

Background:

Placenta accreta involves abnormal placental implantation into the uterine wall.
It is often diagnosed postpartum after failed placental delivery, risking massive hemorrhage and hysterectomy.

Observation:

A case of placenta accreta in a primiparous patient with pre-existing multinodular leiofibromyomatosis (uterine fibroids) is presented.
The patient experienced failed manual removal of a retained placenta.

Findings:

Conservative management was employed for a hemodynamically stable patient desiring future fertility.
Treatment involved unilateral prophylactic uterine artery embolization, a multidose methotrexate regimen, and subsequent abdominal myomectomy.

Implications:

This approach offers a fertility-sparing alternative to hysterectomy in select placenta accreta cases.
Management of placenta accreta in patients with uterine fibroids requires careful consideration.